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Hermanova, Ivana ; Zuñiga-García, Patricia ; Caro-Maldonado, Alfredo ; Fernández Ruiz, Sonia ; Salvador, Fernando ; Martín-Martín, Natalia ; Zabala-Letona, Amaia ; Nuñez-Olle, Marc ; Torrano, Verónica ; Camacho, Laura ; Lizcano, José M. ; Talamillo, Ana ; Carreira, Suzanne ; Gure, Bora ; Cortazar, Ana R. ; Guiu, Marc ; López, José I. ; Martinez-Romero, Anabel ; Astobiza, Ianire ; Valcarcel-Jimenez, Lorea ; Lorente Pérez, Mar ; Arruabarrena-Aristorena, Amaia ; Velasco Díez, Guillermo ; Gomez-Muñoz, Antonio ; Suarez-Cabrera, Cristian ; Lodewijk, Iris ; Flores Landeira, Juana M. ; Sutherland, James D. ; Barrio, Rosa ; De Bono, Johann S. ; Paramio, Jesús M. ; Trka, Jan ; Graupera, Mariona ; Gomis, Roger R. ; Carracedo, Arkaitz | The Company of Biologists | 2020-03-27Gene dosage is a key defining factor to understand cancer pathogenesis and progression, which requires the development of experimental models that aid better deconstruction of the disease. Here, we model an aggressive form of prostate cancer and[...]texto impreso
Pulido, Rafael ; Baker, Suzanne J. ; Barata, Joao T. ; Carracedo, Arkaitz ; Cid, Víctor J. ; Chin-Sang, Ian D. ; Davé, Vrushank ; Hertog, Jeroen den ; Devreotes, Peter ; Eickholt, Britta J. ; Eng, Charis ; Furnari, Frank B. ; Georgescu, María Magdalena ; Gericke, Arne ; Hopkins, Benjamin ; Jiang, Xeujun ; Lee, Seung Rock ; Lösche, Mathias ; Malaney, Prerna ; Matias Guiu, Xavier ; Molina, María ; Pandolfi, Pier Paolo ; Parsons, Ramon ; Pinton, Paolo ; Rivas, Carmen ; Rocha, Rafael M. ; Rodríguez, Manuel S. ; Ross, Alonzo H. ; Serrano, Manuel ; Stambolic, Vuk ; Stiles, Bangyan ; Suzuki, Akira ; Tan, Seong Seng ; Tonks, Nicholas K. ; Trotman, Lloyd C. ; Wolff, Nicolas ; Woscholski, Rudiger ; Wu, Hong ; Leslie, Nicholas R. | American Association for the Advancement of Science | 2014-07-01The tumor suppressor PTEN is a major brake for cell transformation, mainly due to its phosphatidylinositol 3,4,5-trisphosphate [PI(3,4,5)P3] phosphatase activity that directly counteracts the oncogenicity of phosphoinositide 3-kinase (PI3K). PTE[...]
