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Tomé Amat, Jaime ; Olombrada Sacristán, Miriam ; Ruiz de la Herrán, Javier ; Pérez Gómez, Eduardo ; Andradas Arias, Clara ; Sánchez García, Cristina ; Martínez, Leopoldo ; Martínez del Pozo, Álvaro ; Gavilanes, José G. ; Lacadena, Javier | Elsevier | 2015-04Tagging of RNases, such as the ribotoxin ?-sarcin, with the variable domains of antibodies directed to surface antigens that are selectively expressed on tumor cells endows cellular specificity to their cytotoxic action. A recombinant single-cha[...]texto impreso
Tomé-Amat, Jaime ; Ruiz de la Herrán, Javier ; Martínez del Pozo, Álvaro ; Gavilanes, José G. ; Lacadena, Javier | Wiley | 2015-04Toxins have been thoroughly studied for their use as therapeutic agents in search of an improvement in toxic efficiency together with a minimization of their undesired side effects. Different studies have shown how toxins can follow different in[...]
