texto impreso

Reduced apurinic/apyrimidinic endonuclease 1 activityand increased DNA damage in mitochondria are relatedto enhanced apoptosis and inflammation in the brainof senescence- accelerated P8 mice (SAMP8)

Torregrosa Muñumer, R. ; Gómez, A. ; Vara, E. ; Kireev, R. ; Barja de Quiroga Losada, Gustavo ; Fernández Tresguerres Hernández, Jesús Ángel ; Gredilla, R. | Springer Link | 2016

The senescence- accelerated mouse prone 8 (SAMP8) is a well- characterized animal model of senescence that shows early age- related neurodegeneration with impairment in learning and memory skills when compared with control senescence- resistant [...]

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